Dr. John Sanford

Retired Cornell Geneticist, Education: Ph.D. in Plant Breeding and Genetics, President of Logos Research Associates, President of FMS Foundation. 

Biography:

As a Cornell University professor, John conducted genetic research for over 30 years. This research has resulted in more than 100 scientific publications and several dozen patents. In addition to producing numerous new crop varieties, John's research resulted in new genetic engineering technologies. A large fraction of the transgenic crops grown in the world today involved use of the biolistic “gene gun” process, of which John was the primary inventor.

 

John feels his most significant contributions to science have been: 1) the Biolistic Process; 2) the book Genetic Entropy and the Mystery of the Genome; 3) Development of Mendel's Accountant (the most advanced and biologically realistic numerical simulation of the mutation/selection process); and the Cornell symposium and subsequently published proceedings entitled Biological Information--New Perspectives. This milestone book is John's most significant contribution to science and is available at BINP.orgA free synopsis/commentary of this publication can be downloaded using the same link. 

 

Links to Selected Papers:

​​

           -Biological Information and Genetic Theory: Introductory Comments

-Multiple Overlapping Genetic Codes Profoundly Reduce the Probability of Beneficial Mutation 

-Can Purifying Natural Selection Preserve Biological Information

           -Selection Threshold Severely Constrains Capture of Beneficial Mutations

           -Using Numerical Simulation to Test the “Mutation-Count” Hypothesis

           -Can Synergistic Epistasis Halt Mutation Accumulation? Results from Numerical Simulation

           -Computational Evolution Experiments Reveal a Net Loss of Genetic Information Despite        

            Selection

           -Information Loss: Potential for Accelerating Natural Genetic Attenuation of RNA Viruses

 

Books and Chapters:

 

Website Links:

 

© 2020 LogosResearchAssociates.org